NASOSTOP® nasal spray, 1 ST

NASOSTOP® is an aqueous solution made from the natural extract of fresh Cyclamen europaeum L. tubers. NASOSTOP® is a nasal spray that drains accumulated mucus and clears the nose and sinuses.

Innovative mechanism of action

Activates the physiological (natural) cleansing mechanisms of the nasal mucosa, which remove the accumulated mucus from the nose and sinuses.

• Stimulates the receptors in the nasal mucosa. The stimulus is transmitted to the trigeminal nerve endings. The function of the cilia is restored and the production of clear mucus is increased. This increased secretion enables intensive natural cleansing of the paranasal sinuses.
• Draws the fluid contained in the cells of the nasal mucosa (osmotic effect), which liquefies the secretion and facilitates its drainage. This reduces inflammation without irritating or drying out the mucous membrane.

NasoStop - the quick solution for rhinosinusitis

• Allows accumulated mucus to drain away
• Immediate onset of action
• Faster recovery
• Significant reduction in symptoms and recurrence rate ¹
• Clinically proven efficacy (included in the EPOS 2020 guidelines (European Position Paper on Rhinosinusitis and Nasal Polyps)
• Co-medication is often not necessary
• No habituation effect, no rebound effect
• Avoidance of unnecessary use of antibiotics for uncomplicated sinusitis

Properties

• Allows accumulated mucus to drain naturally ➔ Secretions are liquefied ➔ Function of the cilia is restored
• Rapid relief from the first application
• Shortens the time to recovery
• 100% natural with the power of cyclamen
• Adults and children aged 12 and over
  

Who can I recommend NasoStop to?

• Patients: with nasal congestion; with sinusitis; with chronic sinusitis; NOT with runny nose
• Phytotherapy-affine persons with sinusitis
• Patients with nasal congestion and/or sinusitis who want to avoid decongestant nasal sprays

¹ Lopatin et al, 2018 ACTA Otorhinolaryngologica Italica - Official Journal of the Italian Society of Otorhinolaryngology

Dosage form

Nasal spray

Directions for use

NASOSTOP® may only be used in the nose. Follow the instructions below and refer to the illustrations for mixing the ingredients of the product before spraying it into the nostrils.

DO NOT INHALATEduring use as this may increase itching, burning, sneezing, tearing or increased nasal secretions; these are normal and temporary side effects of the mechanism of action of NASOSTOP® PLEASE READ THIS PACKAGE SHEET CAREFULLY BEFORE USING NASOSTOP®.

Preparation of the solution:

1. Open the vial containing the powder (A). To do this, turn the outer cap anti-clockwise and remove the inner cap.
2. Break off the upper part of the plastic ampoule containing the water (B).
3. Empty the entire liquid (B) into the vial with the powder (A).
4. Screw the spray head onto the vial (A) and shake it gently until the contents have completely dissolved. Wait until the foam has disappeared.
5. Remove the protective cap from the spray head.
6. Actuate the spray head 2 to 3 times before the first application in the nose and spray away from the body into the air. Do not allow to get into the eyes.

Administration of Nasostop:

1. Hold your head upright without tilting it backwards or forwards. Insert the spray head into the right nostril. Inhale deeply, hold your breath briefly (3-5 seconds) and administer the solution into the right nostril by pressing the spray head once. Breathe out completely through the mouth once and then continue breathing normally. Do not inhale the product while spraying.
2. Then repeat the procedure under point 7 in the left nostril.
3. Wipe the spray head with a clean cloth. Replace the protective cap on the spray head.

Precautions before using Nasostop: If you are taking anticoagulants and/or anticholinergics, consult your doctor before using NASOSTOP®. The solution obtained from the mixture should only be sprayed into each nostril once a day, preferably at the same time of day, about 2 hours before going to bed. More frequent use than once a day does not result in greater efficacy and should be avoided. The spray should be used over a period of 7 to 10 days, up to 14 days if necessary. After that, 7 to 10 treatment-free days should be allowed before the product is used again. NASOSTOP® can be used in adults and children over 12 years of age. Use in children must be under the supervision of an adult. NASOSTOP® must not be used if you are allergic (hypersensitive) to cyclamen, primroses or other plants of the Primulaceae family.

Precautions when using the product: Contact your doctor if your symptoms do not improve after 10 days or worsen after 5 days. Tell your doctor or pharmacist if you notice any side effects or unexpected effects not listed in this leaflet. Ask your pharmacist if you need more information about the product. We recommend that you do not drive or operate machinery for two hours after taking NASOSTOP®. NASOSTOP® is best used two hours before going to bed.

Important information: A few minutes after administration, you may feel a brief, temporary mild itching, a burning sensation in the nasopharynx, sneezing, lacrimation and increased nasal secretions. These are signs of a positive response to the product; although they may cause mild discomfort for a short time, they are expected reactions. A pink-coloured nasal discharge may also occur. This is normal and not a cause for concern. It is recommended to remove the product from the refrigerator two to three minutes before use to reduce the intensity of the adverse effects mentioned above, as they are partly due to cold. Return the product to the refrigerator immediately after use. Do not inhale during nebulisation as this may intensify and prolong the effects mentioned above.

Ingredients

Each pack of NASOSTOP® contains:

• 1 vial (A) of freeze-dried cyclamen extract
• 1 ampoule (B) with water to dissolve the lyophilisate
• 1 spray head for atomising the solution

Qualitative and quantitative composition:

• Vial A: Freeze-dried extract of Cyclamen europaeum L., 50 mg.
• Vial B: Water, 5 ml.