The PRIMA® Urinary Tract Infection Home Test is a self-test for the detection of leucocytes, blood, nitrites and proteins in urine. Result after only 2 minutes.
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- Leucocytes: This test indicates the presence of granulocyte esterases. The esterases cleave a derivatised pyrazole amino acid ester, thereby releasing hydroxylpyrazole. This pyrazole then reacts with a diazonium salt to produce a beige-pink to violet colour.
- Blood: This test is based on a peroxidase-like activity of haemoglobin, which catalyses the reaction between diisopropylbenzene dihydroperoxide and 3,3’,5,5’-tetramethylbenzidine. The resulting colour ranges from orange through green to dark blue.
- Nitrite: This test is based on the conversion of nitrate to nitrite by Gram-negative bacteria in the urine. In an acidic environment, nitrite in the urine reacts with p-arsanilic acid to form a diazonium compound. The diazonium compound, in turn, binds to 1N-(1-naphthyl)-ethylenediamine to produce a pink colour.
- Protein: This reaction is based on the phenomenon known as the ‘protein error’ of pH indicators, whereby a strongly buffered indicator changes colour in the presence of proteins (anions), as the indicator donates hydrogen ions to the protein. The colours range from yellow to yellow-green for negative results and from green to green-blue for positive results.
- Leukocyte accuracy 97.6%
- Blood accuracy 96.0%
- Protein accuracy 88.0%
- Nitrite accuracy 100.0%
Presentation
Instructions
- Collect your first morning urine in a dry, clean container;
- Remove the test strip from the foil pouch;
- Dip the test strip into the sample for 1–2 seconds;
- Wait 2 minutes to read the result.
- Negative: No leukocytes, blood, nitrites or proteins were detected in the urine.
- Positive for leukocytes: Leukocytes have been detected in the urine. It is recommended that you consult your doctor.
- Positive for blood: Blood has been detected in the urine. It is recommended that you consult your doctor.
- Positive for nitrites: Nitrites have been detected in the urine. It is recommended that you see your doctor.
- Positive for protein: Protein has been detected in the urine. It is recommended that you see your doctor.
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