Ostenil® Mini 10mg/1ml prefilled syringe, 1 ST

OSTENIL® MINI Sodium hyaluronate from fermentation 1.0%. Viscoelastic solution for injection into small joints. Sterile due to moist heat.

Indications

• Pain and restricted mobility in degenerative and traumatic changes to small synovial joints, such as the facet joints of the lumbar spine, the thumb saddle joint, the interphalangeal joints of the fingers and toes, the metatarsophalangeal joint of the big toe and the temporomandibular joint. For the treatment of large joints, such as the knee, hip or shoulder joint, OSTENIL® prefilled syringes of 20 mg/2.0 ml should be used.

Properties and mode of action

• Synovial fluid, which is viscoelastic due to its hyaluronic acid content, is found in all synovial joints, where its lubricating and shock-absorbing properties ensure normal, pain-free movement. It is also responsible for supplying the joint cartilage with nutrients. In degenerative joint diseases, such as osteoarthritis, the viscoelasticity of synovial fluid is significantly impaired, which reduces its lubricating and shock-absorbing effect. As a result, the mechanical load on the joint and the degradation of the joint cartilage increase to such an extent that pain and limited mobility occur in the affected joint.
• Improving the quality of the synovial fluid by intra-articular administration of high-purity hyaluronic acid can improve the viscoelastic properties of the synovial fluid. This improves its lubricating and shock-absorbing effect and reduces the mechanical overloading of the joint. The result is usually a reduction in pain and an improvement in joint mobility, which can last for several months after a treatment cycle.

Dosage form

injection

How to use

Inject OSTENIL® MINI into the affected joint 1-3 times at weekly intervals. Several joints can be treated at the same time. Depending on the severity of the joint disease, the effect of a treatment can last for more than six months. Repeated treatment cycles are possible if necessary. If a joint effusion is present, it is advisable to puncture the effusion, immobilise the joint and apply an ice pack and/or administer corticosteroids intra-articularly. Two to three days later, treatment with OSTENIL® MINI is started.

As long as the sterile packaging has not been opened, the contents and the surface of the prefilled syringe are sterile. The prefilled syringe is removed from the sterile packaging, the cap is unscrewed from the Luer lock connection, a suitable cannula (e.g. 19 to 25 G) is attached and locked in place by turning it slightly. Before the injection, any air bubble is removed from the syringe.

Ingredients

1 ml isotonic solution contains 10.0 mg sodium hyaluronate as well as sodium chloride, disodium hydrogen phosphate, sodium dihydrogen phosphate and water for injection.